Fri Jan 23 2026

130 articles - From Friday Jan 16 2026 to Friday Jan 23 2026

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Guidelines

Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…


Meta-analysis

meta-analyses and systematic reviews

Clin Gastroenterol Hepatol
Endovascular interventions reduce rebleeding in patients with gastric varices: An individual patient data meta-analysis.

Endovascular interventions (BRTO and TIPS) are superior to ECI for reducing all-cause rebleeding in patients with cirrhosis and GV hemorrhage. Larger studies with standardized end-points and long-term outcomes are needed to clarify survival benefit and optimize treatment selection.

Pubmed   Journal   ReadQx 

Impact of 20% Change in VCTE-measured Liver Stiffness on Liver-related Outcomes: A systematic Review and Meta-Analysis.

Dynamic LSM changes in no-cACLD progressors and cACLD regressors are significantly associated with increased and decreased LRE risk, respectively. These findings highlight the potential of serial LSM measurements for monitoring chronic liver disease and for clinical trial endpoints. Prospective longitudinal studies are needed to evaluate if changes in LSM measurements over time are linked to improved patient outcomes.

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Gastrointest Endosc
CLINICAL RESPONSE TO GASTRIC PERORAL ENDOSCOPIC MYOTOMY AND ITS ASSOCIATION TO CHANGES IN PYLORIC IMPEDANCE PLANIMETRY MEASUREMENTS: A SYSTEMATIC REVIEW AND META ANALYSIS.

Our analysis shows that patients who responded to G-POEM had higher baseline GCSI scores when compared to non-responders. Post-G- POEM pylorus CSA was associated with clinical response. FLIP may provide objective assessment of pyloric changes and be a potential tool to predict clinical outcome of G-POEM. Additional studies with standardized FLIP protocols in patients undergoing G-POEM are needed.

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Original articles

RCT, clinical trials, retrospective studies, etc…

Am J Gastroenterol
Addiction in Gastrointestinal and Liver Disorders.

Medications for alcohol use disorder and opioid use disorder are underutilized despite strong evidence for safety and efficacy, even in patients with hepatic dysfunction. Gastroenterologists and hepatologists are often well-positioned to identify and address substance use disorders early and should strive to provide coordinated care that improves both addiction and GI/liver-related outcomes.

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An Artificial Intelligence-Guided Strategy to Reduce Poor Bowel Preparation: A Multicenter Randomized Controlled Study.

A software application-driven colon cleansing process improves preparation quality in outpatients (NCT05871814).

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Cost-effectiveness of first-line regimens for Helicobacter pylori infection in the United States.

BQT was found to be the cost-effective first-line treatment. Rifabutin triple therapy was a cost-effective alternative. Policymakers should prioritize BQT and rifabutin triple therapy versus other therapies.

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Ethical and Practical Considerations for Mental Health Screening in Adult Patients with Inflammatory Bowel Disease.

The implementation of routine mental health screening for adults with IBD aligns with core ethical principles and supports comprehensive biopsychosocial care. With thoughtful implementation, gastroenterology practices can improve identification of depression and anxiety and facilitate timely access to appropriate mental health services.

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Low-dose aspirin continuation during gastric ESD in patients with low thrombotic risk: a randomized trial.

The non-inferiority of LDA continuation over discontinuation for ESD-related major bleeding in gastric ESD was not demonstrated. Therefore, discontinuation of LDA during the periprocedural period is recommended for patients with low thrombotic risk. (UMIN000013177).

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Machine Learning Model Predicts Recurrent Clostridioides difficile Infection in Patients With Inflammatory Bowel Disease (Recur CDI-IBD).

The RecurCDI-IBD model demonstrates good discriminatory ability with balanced precision and recall in identifying IBD patients at higher risk for recurrent CDI. These findings highlight the potential of data-driven approaches to support clinical risk assessment. Further studies incorporating larger and more diverse cohorts and prospective external validation are needed to confirm generalizability and optimize clinical applicability.

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Treatment Delays and Survival in Patients with Hepatocellular Carcinoma: A Multicenter Cohort Study.

Treatment delays exceeding 90 days occurred in over one-fifth of patients but were not associated with significant differences in survival.

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Clin Gastroenterol Hepatol
Serum IgG Response to a Conserved Domain of Commensal Flagellins Predicts Future Risk of Crohn's Disease in First-Degree Relatives.

Increased antibody response in healthy FDRs towards Lachnospiraceae flagellins is associated with future risk of CD. Importantly, pre-CD subjects shared seroreactivity towards a conserved bacterial flagellin epitope, which may represent an early pre-clinical biomarker of CD.

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Endosc Int Open
Anchoring of esophageal stents with through-the-scope suturing devices: Preclinical proof of concept and first clinical cases.

This is the first preclinical and clinical description of the benefits of TTSS for FCSEMS anchoring in esophageal refractory benign strictures. Safe and efficient anchoring with TTSS could allow using double-silicon-layered FCSEMS that can be left in place several months for management of refractory benign strictures. This work paves the way for prospective studies assessing FCSEMS anchoring with TTSS.

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Assessment of early gastric cancer visibility in deep-learning-based virtual indigo carmine chromoendoscopy (with video).

Virtual IC improved visibility compared with WLE in nearly half the assessments, although its efficacy did not equal real IC. Optimizing performance for specific endoscope systems may enhance its clinical utility as a practical alternative for improving EGC detection.

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Automated assessment of small bowel and colon cleansing in enteroscopy using a convolutional neural network.

Current bowel cleanliness assessment methods are subjective and region-specific. This study presents the first CNN capable of panendoscopic bowel cleanliness evaluation during DAE, achieving high accuracy and demonstrating potential for real-time clinical application. This study marks a key step toward standardizing cleanliness assessment and endoscopy quality improvement.

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Clinical outcomes of circumferential endoscopic submucosal dissection in esophageal squamous cell carcinoma > 50 mm: Retrospective cohort study.

Results Stricture incidence was not significantly different (> 50 mm vs ≤ 50 mm: 13% vs 18%, 50 mm did not increase adverse events and provided comparable long-term survival. These findings support feasibility beyond guideline limits and emphasize further refinement of stricture prevention.

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Comparison of adenoma detection rate using the novel 5-LED vs xenon-light endoscopic system: Propensity score matching analysis.

The EVIS X1 system may have the potential to improve adenoma detection, particularly when used with CMOS sensor-equipped scopes. These findings suggest potential benefits for colorectal cancer screening, although further large-scale studies are warranted for validation.

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Endoscopic necrosectomy is safe in patients with pancreatic walled-off necrosis: Insights from a tertiary center study of 880 procedures.

AEs are rare in EN but are associated with increased mortality.

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Endoscopic ultrasound molecular evaluation of pancreatic cancer trial to profile molecular landscape of inoperable pancreatic ductal adenocarcinoma.

This real-world study confirms the feasibility and utility of CGP using EUS-FNB in advanced PDAC. It illustrates the importance of timely access to personalized therapy informed by CGP, which can impact the treatment pathway and improve survival outcomes.

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Enhancing emergency endoscopy efficiency with an additional suction channel: In vitro assessment.

A standard gastroscope equipped with an ASC significantly enhances suction performance in an in vitro model, outperforming gastroscopes with larger working channels. These findings warrant further validation in an ex vivo model to determine their clinical applicability.

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Identifying high-risk patients having ERCP as a day surgery with an online prediction platform: Multicohort validation of a machine learning model.

The results indicate that the proposed LR model, utilizing the top seven risk factors, could serve as an effective tool for predicting occurrence of complications in day surgery.

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Multicenter study of colon capsule endoscopy in post-polypectomy surveillance.

CCE is a safe diagnostic of colorectal polyps. In surveillance, its "filter function" complements existing colorectal diagnostic services by providing capacity and choice.

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Neoplastic risk in hyperplastic esophagogastric junction lesions: Comprehensive multicenter study.

EGJ hyperplastic lesions showed a non-negligible risk of neoplastic transformation. These findings highlight the need for careful endoscopic assessment to predict malignancy while promoting appropriate management strategies to ensure adequate R0 resection in case of undetected local malignancy.

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Technical aspects of endoscopic internal drainage procedure, secured by endoscopic suture fixation: Experimental study.

In conclusion, this study demonstrates the conceptual possibility of using an endoscopic needle holder for suture-fixation of a drain. Further clinical investigations are required to establish a full feasibility test of the concept.

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Endoscopy
Approaches to assessing completeness of polyp resections in clinical practice: a systematic scoping review.

Different methods are available to assist in visual confirmation of complete resection and measuring IRRs, with considerable variability in their application. This review highlights the need for standardized assessment of complete colorectal polyp resection.

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Gastroenterology
ENPP1-Regulated Extracellular Purine Metabolism Drives Pancreatitis-Mediated Pancreatic Cancer.

The study results identified ENPP1 as a contributor to pancreatitis-mediated pancreatic cancer and a potential therapeutic target for pancreatic carcinogenesis.

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Faecalibacterium prausnitzii Induces an Anti-inflammatory Response and a Metabolic Reprogramming in Human Monocytes.

F prausnitzii induces an anti-inflammatory response and rewires energy metabolism in human monocytes in healthy and inflamed conditions, potentially explaining its beneficial impact on intestinal inflammation and human health in general. These results provide new insight into the mechanisms underlying the anti-inflammatory effects of F prausnitzii and are crucial for a better understanding of its potential use in IBD treatment.

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Utility of Serum Biomarkers in Addition to Ultrasound for Early Detection of Hepatocellular Carcinoma in High-Risk Patients: A Randomized Controlled Trial.

Addition of AFP, AFP-L3, and DCP to biannual US did not improve early-stage HCC detection. The trial was not adequately powered to provide evidence that the use of BMs aside from US plus AFP improves HCC surveillance. Establishing and validating alternative approaches to incorporation of BMs may improve surveillance methods for early-stage HCC detection. , Number NCT02272504.

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Gastrointest Endosc
Computer Aided Polyp Detection Multi-center International Randomized Controlled Study with a Focus on Community Clinics: GAIN Clinical Trial.

These results support the incorporation of CADe devices into colonoscopy practice for improving efficacy and quality over standard-of-care, particularly in community practices.

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EUS-guided ethanol lavage as a novel therapeutic modality for symptomatic simple renal cysts.

EUS-EL appears technically feasible and safe for treating simple renal cysts, with preliminary results supporting further evaluation in larger prospective studies.

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Fluoroscopy-free Direct Solitary Cholangioscopy versus Endoscopic Retrograde Cholangiography for Clearance of Noncomplex Biliary Stones: A Noninferiority Randomized Controlled Trial.

Clearance rates of noncomplex biliary stones and rates of SAEs were comparable for ERC versus fluoroscopy-free DSC, with lower exposure to fluoroscopy-associated radiation during DSC. (ClinicalTrials.gov no. NCT03421340).

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Long-term Outcomes of EUS-guided Gastroenterostomy (LONG-RANGE study): a prospective cohort study tracking symptom recurrence, reintervention timelines and stent modifications over time.

Clinically overt EUS-GE dysfunctions are rare and successfully endoscopically amenable, discouraging scheduled surveillance in malignancies. However, LAMS shows predictable narrowing, sustained by subclinical local reactions, which might inform surveillance in benign indications.

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Prospective cohort study of palliative treatment of esophageal cancer with liquid nitrogen spray cryotherapy.

Spray cryotherapy had a durable and repeatable benefit for palliation of obstructive symptoms of esophageal cancer and quality of life in the majority of patients, without the need for feeding tube or esophageal stent placement. Treatments were generally well-tolerated.

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The 2025 top 10 list of endoscopy topics in medical publishing: an annual review by the American Society for Gastrointestinal Endoscopy Editorial Board.

The top 10 identified topics collectively represent advances in the following endoscopic areas: endoscopic GERD therapies, non-variceal GI bleeding, endo-oncology, endo-hepatology, vacuum therapy, colonoscopy prep primer, polypectomy best practices, metabolic and bariatric endoscopy, third space endoscopy, and AI applications in endoscopy. Board members were each assigned a topic area and summarized relevant and important articles, thereby generating this overview of the "top 10" endoscopic advances of 2025.

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Gut
Associations between demographic, clinical and dietary factors and flares in inflammatory bowel disease: the PRognostic effect of Environmental factors in Crohn's and Colitis (PREdiCCt) prospective cohort study.

Higher habitual meat intake was associated with increased risk of objective flare in UC, suggesting diet may contribute to flare susceptibility in specific patient groups.

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Complement-secreting CAFs are associated with better prognosis in pancreatic cancer: single-cell multiomics.

Our study demonstrates that csCAFs may represent an early-stage iCAF subtype and suggests a promising strategy for reprogramming iCAFs into csCAFs.

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Genetic dissection of stool frequency implicates vitamin B1 metabolism and other actionable pathways in the modulation of gut motility.

We identify therapeutically tractable mechanisms involved in the control of gut motility, including a previously unrecognised role for vitamin B1. These findings warrant mechanistic and clinical studies to evaluate their translational potential in IBS and other dysmotility syndromes.

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LY6D identifies persistent stem-like cells driving pancreatic tumourigenesis.

Our work defines the LY6D + gastric-like cell state as a key driver linking early pre-malignant heterogeneity to PDAC initiation and progression. LY6D represents a pan-stage therapeutic target and a candidate biomarker for early detection and therapeutic targeting.

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Oncological impact of universal endoscopic submucosal dissection for large Barrett's cancers.

Period 2 had a higher cancer burden (52.3% vs 34.9%) and greater ESD use (77.1% vs 21.2%). Basal R0 resection improved from 69.7% to 91.2% (p 15 mm improves basal R0 resection, reduces recurrence and improves short-term survival for T1b disease, supporting routine ESD for al larger Barrett's cancers.

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Steatosis grade and cardiometabolic burden as determinants of hepatocellular carcinoma risk after hepatitis C cure in patients with metabolic dysfunction-associated steatotic liver disease.

Advanced hepatic steatosis and glycaemic abnormalities, rather than overall cardiometabolic burden, are independently associated with increased HCC risk after HCV cure.

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Targeting ADAR1-mediated RNA editing inhibits hepatic stellate cell activation and liver fibrosis by enhancing HSC-intrinsic innate immunity.

ADAR1-imposed RNA editome suppresses HSC-intrinsic innate immunity and promotes collagen production, leading to aggravated HSC activation and liver fibrosis. Targeting ADAR1 with its pharmacological inhibitor or HSC-selective RNAi shows great promise in treating liver fibrosis.

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Zinc-dependent RNA-binding protein controls hepatocyte senescence and recovery from alcohol-related liver failure.

These findings uncover a zinc-dependent ZFP36L1-regulon that governs hepatocyte fate by repressing p21- and JAG1-driven senescence and NOTCH activation and highlight ZFP36L1 as a promising therapeutic target in ALD.

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Hepatology
Biologically explicable multimodal model predicting local tumor progression and tumor invasiveness of hepatocellular carcinoma.

Multimodal model achieved satisfactory performance on classifying tumor invasiveness, and provided effective strategy for high-invasiveness tumor to reduce LTP occurrence.

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NRF2-COX2-PGE2 axis drives immune cold tumors and predicts resistance to combination immunotherapy in hepatocellular carcinoma.

Tumor-intrinsic activation of the NRF2-COX2-PGE₂ axis drives immune cold TMEs and mediates Atez/Bev resistance in HCC. Targeting this pathway may enhance efficacy, and plasma PGE₂ represents a non-invasive biomarker for stratification.

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J Hepatol
Single nucleotide polymorphisms in the bepirovirsen binding site have limited impact on treatment response in chronic hepatitis B.

The majority of participants achieved >1 log HBsAg reductions, including transient HBsAg loss in some, though numerically smaller HBsAg reductions in participants with baseline SNPs require further investigation to better understand resistance mechanisms to bepirovirsen. Impacts and implications HBV sequence polymorphisms can lead to antiviral resistance for the treatment of chronic HBV infection. Therefore, it is important for HCPs to understand the prevalence and development of bepirovirsen binding site SNPs and how their presence in patients with chronic HBV infection may impact the virological response to bepirovirsen treatment. The Phase 2b clinical study findings reported here show that the large majority (92%) of non-responders, partial responders or relapsers did not have bepirovirsen binding site SNPs. Those with bepirovirsen binding site SNPs (7% of participants) still achieved HBsAg reductions, indicating that there is no need at this stage to test for specific HBV variants when administering bepirovirsen, and that treatment resistance via a change in sequence complementarity may be minimal and likely multifactorial. Additional data from ongoing Phase 3 studies of bepirovirsen will provide additional context for assessing this need, and for understanding potential mechanisms of resistance to bepirovirsen.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link

Aliment Pharmacol Ther
Editorial: Linking Patients With Cirrhosis to Clinical Care-The Hurdles and Way Forward.

Pubmed   Journal   ReadQx 

Editorial: TIPS in the Era of Aging and Metabolic Comorbidity: Rethinking Risks and Rewards.

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Review Article: Classic Bismuth Quadruple Therapy for Helicobacter pylori Infection-Questions Focused on Clinical Practice.

BQT remains the most effective, safe, and practical regimen for H. pylori eradication, ensuring high cure rates across diverse resistance patterns and clinical settings. Simplified formulations further improve convenience and adherence, reinforcing its role as a globally applicable therapy.

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Review Article: Drug Approval for Gastroparesis-Suggestions for Improving the Process for Positive Results.

The evidence documented here justifies consideration of gastroparesis as an orphan disease, as well as an innovative approach to supplement the regulatory bodies' recommendations and guidance to industry. We propose treatment trials of 4-weeks duration and considering the use of specific symptoms of gastroparesis as clinical endpoints based on a pharmaceutical agent's mechanism of action, rather than using a total gastroparesis symptom score. Such an approach would include evidence of safety and efficacy of new medications targeting gastroparesis subscales, and approval for marketing would be based on the symptoms specifically ameliorated in robust trials.

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Gastroenterology
Is a Goldilocks Solution for Colorectal Cancer Screening Just a Fairy Tale? Overdiagnosis Versus Later Diagnosis of Premalignant Lesions.

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Understanding Polyposis Development: Progress and the Many Remaining Challenges.

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Gastrointest Endosc
A note from the Editor-in-Chief.

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Barotrauma perforation at colonoscopy: potentially disastrous but preventable.

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Endoscopic submucosal dissection for anal canal lesions: Expanding the frontiers or stretching the limits?

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Endoscopic ultrasound-guided choledochoduodenostomy without the need for dilation: Shortening the shortcut!

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Melius abundare quamdeficere! Adding base ablation to margin ablation may further reduce the risk of residual or recurrence adenoma.

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Pancreatic fluid collections in 3 dimensions: seeing is revealing.

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Shedding light on refractory pancreaticobiliary strictures: the emerging role of laser dissection.

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Sometimes less is less: endoscopic submucosal resection with band ligation of rectal neuroendocrine tumors with and without submucosal injection.

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Stent savvy: a step toward clarity in navigating metallic stent choice for malignant biliary obstruction.

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To fin or not to FIN: a tale of 2 stents.

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Why rectal cancer deserves a standalone spotlight.

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J Hepatol
Is liver steatosis a disease or the emperor's new clothes?

Recognising the differentiation between steatosis (not a standalone liver disease) and MASH/fibrosis (true driver of liver-related risk) enables more precise risk communication, guides targeted surveillance and therapy, and prevents unnecessary alarm or wasting resources in strained healthcare systems. This paradigm shift supports credible, evidence-based public health strategies focused on metabolic health and fibrosis prevention.

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Standing on the shoulders of giants.

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Miscellaneous

misc publications eg case reports, tools of the trade, images of the month, etc…

Am J Gastroenterol
Autoimmune Hepatitis and Depression.

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Correction to: Clinical Evolution, Complications, and Need for Advanced Therapy in Patients With Ulcerative Colitis (Abstract S2018); Pioneering Minimally Invasive Management of Pancreatic Neuroendocrine Tumor: First EUS-RFA Case in Colombia (Abstract S3312); and Jejunal Diverticulum With Arteriovenous Malformation (Abstract S4758).

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Correction to: Randomized, Double-Blind, Active-Controlled Phase 3 Study to Evaluate Efficacy and Safety of Zastaprazan Compared to Esomeprazole in Erosive Esophagitis.

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Gallstone Ileus: A Rare Complication of EUS-Guided Gallbladder Drainage.

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Letter to the Editor.

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Response to Rao et al.

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Reviewer Recognition.

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Endosc Int Open
Clip-assisted anchoring method to facilitate submucosal tunnel entry in peroral endoscopic myotomy for severe fibrosis.

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Laser stricturotomy-assisted rendezvous ERCP and cholangioscopy for post-cholecystectomy complete common bile duct transection.

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Endoscopy
A case of massive hemobilia during plastic stent exchange following distal pancreatectomy with celiac axis resection and carbon-ion radiotherapy.

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A rare case of endoscopically removing a fractured pancreatic stent related to surgery.

Pubmed   Journal   ReadQx   PMC

A simplified strategy for stent fixation using a defect-closure system in refractory esophageal stricture.

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Cholangioscopy-guided laser lithotripsy alongside a plastic stent for common bile duct stones after total gastrectomy.

Pubmed   Journal   ReadQx   PMC

Direct-view endoscopic ultrasound-guided fibrotic hepaticojejunostomy stricture managed with a modified stent tube.

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Effectiveness of immediate contrast-enhanced evaluation after endoscopic ultrasound-guided ethanol injection for a pancreatic neuroendocrine tumor.

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Emergency colonoscopy for rectal ulcer bleeding: argon plasma coagulation failure rescued by underwater snare-tip coagulation and self-assembling peptide hydrogel.

Pubmed   Journal   ReadQx   PMC

Endoscopic submucosal dissection for a retrorectal tailgut cyst: a case report.

Pubmed   Journal   ReadQx   PMC

Endoscopic ultrasound-free lumen apposing metal stent recanalization of a complete ileal J-pouch stenosis restoring intestinal continuity.

Pubmed   Journal   ReadQx   PMC

Endoscopic ultrasound-guided colorectal anastomosis using a lumen-apposing metal stent for complete anastomotic stricture.

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Esophagopleural fistula and candidiasis: endoscopic stent management after steroid-induced perforation.

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Flipping the tumor from outward to inward: simplifying and accelerating endoscopic full-thickness resection.

Pubmed   Journal   ReadQx   PMC

Four-branched hybrid stent placement using multi-hole-covered self-expandable metallic stents for Bismuth type IV malignant hilar biliary obstruction.

Pubmed   Journal   ReadQx   PMC

Identification of an intramuscular gastric subepithelial stromal tumor during endoscopic resection by using endoscopic ultrasound within the submucosal tunnel.

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Innovative resource-limited endoscopy simulator for skill development.

Pubmed   Journal   ReadQx   PMC

Laser ablation for tumor ingrowth of the bridging stent via the endoscopic ultrasound-guided hepaticogastrostomy.

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Laser lithotripsy for refractory stones in the cystic duct and common bile duct.

Pubmed   Journal   ReadQx   PMC

Long-term local tumor control by endoscopic radiofrequency ablation for ampullary carcinoma with biliary extension in a patient with familial adenomatous polyposis.

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Lumen-apposing metal stent fixation using a defect-closure system for the management of a case of afferent limb syndrome.

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Marsupialisation of a tunnel flap for a false oesophageal lumen post peroral endoscopic myotomy.

Pubmed   Journal   ReadQx   PMC

Nasobiliary tube-assisted cholangioscopy-guided electrohydraulic lithotripsy successfully used to treat a difficult common bile duct stone.

Pubmed   Journal   ReadQx   PMC

Overcoming sharp angulation for biliary access with a novel endoscopic retrograde cholangiopancreatography cannula in surgically altered anatomy.

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Preemptive fixation of a jejunal enteral tube extension via novel anchoring system.

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Prophylactic clip closure after colorectal endoscopic submucosal dissection: lessons from a European multicenter analysis and the Japanese experience.

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Tip-in underwater endoscopic mucosal resection for a sessile lesion at a poorly visualized location.

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Gastroenterology
Association Between Serrated Polyps on Index Examination and Advanced Findings Detected on the Second Surveillance Colonoscopy: Data From the New Hampshire Colonoscopy Registry.

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Characteristics of Colonoscopy- and Fecal Immunochemical Test-Based Screen-Detected Premalignant Neoplastic Lesions: Results From the COLONPREV Study.

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HLA Heterozygosity Influences Colorectal Cancer Risk and Survival Outcome.

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MLH1 Lynch Syndrome Colorectal Cancers Are Driven by Heterogeneous Wnt Pathway Gene Mutations.

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Progression of Pancreatic Morphologic Changes and Endocrine Dysfunction After Acute Pancreatitis: Preliminary Results of the Longitudinal Goulash-Plus Cohort Study.

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Hepatology
Alcohol use dominates determining liver related events in steatotic liver disease: Rethinking the role of metabolic dysfunction.

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Fellows' Corner.

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From intuition to index: Combining frailty and comorbidities to stratify liver transplant risk.

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Fueling fibrosis: The PBX1-IL7R axis and its role in hepatic stellate cell activation.

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MASLD: To screen or not to screen-That is the question.

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Metabolic syndrome and cholangiocarcinoma: A signal too strong to ignore.

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Population-level screening for liver disease: Opportunities and challenges.

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J Hepatol
A rare vascular puzzle: Portal hypertension and hepatic lesions.

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From the Editor's Desk...

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Redox-dependent substrate use in hepatic gluconeogenesis shapes exercise performance.

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Tobevibart and elebsiran for the treatment of chronic hepatitis delta.

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Letters&Replies

Letters to the editors and authors’ replies

Aliment Pharmacol Ther
Editorial: TIPS in the Era of Aging and Metabolic Comorbidity-Rethinking Risks and Rewards. Authors Reply.

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Letter: Using Anti-HBs Titers to Tailor HBV Reactivation Monitoring in Patients With Solid Tumours-Authors' Reply.

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Letter: Using Anti-HBs Titres to Tailor HBV Reactivation Monitoring in Patients With Solid Tumours.

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Clin Gastroenterol Hepatol
Addressing the elephant in the room: Herbal liver injury is more severe and catastrophic than liver injury from conventional drugs.

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GEMA-AI and the Ethical Future of Liver Transplantation: Between Survival and Meaningful Outcomes.

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Portal Pressure Measurement: A Question of How or by Whom?

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The DILI-Inpt Prognostic Score.

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Toward More Equitable Liver Allocation: Optimizing the GEMA-AI Model for the Chinese Context.

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Gastrointest Endosc
Does modified peroral endoscopic myotomy really not reduce the incidence of postoperative reflux esophagitis?

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Increased risks associated with large endoscopic sphincterotomy combined with endoscopic papillary large balloon dilation.

Pubmed   Journal   ReadQx 

Optimizing evidence translation for transoral outlet reduction: methodologic considerations and clinical implications.

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Percutaneous sinus tract endoscopic necrosectomy: double-lumen catheters may be more economical and equally safe compared with fully covered metal stents.

Pubmed   Journal   ReadQx 

The hidden advantage: colonoscopy preparation mitigates gastric content risk associated with glucagon-like peptide-1 receptor agonists.

Pubmed   Journal   ReadQx 

Toward a more nuanced evaluation of endoscopic sleeve gastroplasty: beyond biomarkers to clinical meaning.

Pubmed   Journal   ReadQx 

Gut
Clarifying the stopping rule and clinical value of AI-guided PEG titration for bowel preparation.

Pubmed   Journal   ReadQx 

J Hepatol
Is Partial Cure a Realistic Endpoint for Novel Hepatitis B Therapy?

Pubmed   Journal   ReadQx 

Thrombotic microangiopathy or rejection in first pig-to-human patient liver xenotransplantation.

Pubmed   Journal   ReadQx